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17Beta Hydroxysteroid dehydrogenase : ウィキペディア英語版 | 17Beta Hydroxysteroid dehydrogenase
17β-Hydroxysteroid dehydrogenases (, ''beta-hydroxy steroid dehydrogenase'', ''17-ketoreductase'', ''17beta-hydroxy steroid dehydrogenase'', ''3beta-hydroxysteroid dehydrogenase'', ''3beta-hydroxy steroid dehydrogenase'', ''17β-HSD, ''17-ketosteroid oxidoreductases'', ''HSD17B'', ''17-ketosteroid reductases'', ''17-KSR), are a group of alcohol oxidoreductases which catalyse the dehydrogenation of 17-hydroxysteroids in steroidogenesis. This includes interconversion of DHEA and androstenediol, androstenedione and testosterone, and estrone and estradiol, respectively. Note that the major reactions catalysed by 17β-HSD (e.g., the conversion of androstenedione to testosterone) are in fact hydrogenation (reduction) rather than dehydrogenation (oxidation) reactions. ==Genes== Genes coding for 17β-HSD include: * HSD17B1 * HSD17B2 * HSD17B3 * HSD17B4 * HSD17B6 * HSD17B7 * HSD17B8 * HSD17B10 * HSD17B11 * HSD17B12 * HSD17B13 * HSD17B14
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