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17Beta Hydroxysteroid dehydrogenase
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17Beta Hydroxysteroid dehydrogenase : ウィキペディア英語版
17Beta Hydroxysteroid dehydrogenase

17β-Hydroxysteroid dehydrogenases (, ''beta-hydroxy steroid dehydrogenase'', ''17-ketoreductase'', ''17beta-hydroxy steroid dehydrogenase'', ''3beta-hydroxysteroid dehydrogenase'', ''3beta-hydroxy steroid dehydrogenase'', ''17β-HSD, ''17-ketosteroid oxidoreductases'', ''HSD17B'', ''17-ketosteroid reductases'', ''17-KSR), are a group of alcohol oxidoreductases which catalyse the dehydrogenation of 17-hydroxysteroids in steroidogenesis. This includes interconversion of DHEA and androstenediol, androstenedione and testosterone, and estrone and estradiol, respectively.
Note that the major reactions catalysed by 17β-HSD (e.g., the conversion of androstenedione to testosterone) are in fact hydrogenation (reduction) rather than dehydrogenation (oxidation) reactions.
==Genes==
Genes coding for 17β-HSD include:
* HSD17B1
* HSD17B2
* HSD17B3
* HSD17B4
* HSD17B6
* HSD17B7
* HSD17B8
* HSD17B10
* HSD17B11
* HSD17B12
* HSD17B13
* HSD17B14

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
ウィキペディアで「17Beta Hydroxysteroid dehydrogenase」の詳細全文を読む



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